Membrane Transport Inhibition as Mode of Action of Polyene Antimycotics: Recent Data Supported by Old Ones

Recent studies demonstrate that the actual interactions of polyenes with membrane sterols are the basis for their antimycotic toxicity and not, as previously assumed, their potential to form pores. Therefore, sterols must play a vital role in membranes and this function is seriously disturbed once p...

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Bibliographic Details
Main Authors: Miroslava Opekarová, Widmar Tanner
Format: Article
Language:English
Published: University of Zagreb Faculty of Food Technology and Biotechnology 2014-01-01
Series:Food Technology and Biotechnology
Subjects:
Online Access:http://hrcak.srce.hr/file/175199