Information theoretic alignment free variant calling

While traditional methods for calling variants across whole genome sequence data rely on alignment to an appropriate reference sequence, alternative techniques are needed when a suitable reference does not exist. We present a novel alignment and assembly free variant calling method based on informat...

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Bibliographic Details
Main Authors: Justin Bedo, Benjamin Goudey, Jeremy Wazny, Zeyu Zhou
Format: Article
Language:English
Published: PeerJ Inc. 2016-07-01
Series:PeerJ Computer Science
Subjects:
Online Access:https://peerj.com/articles/cs-71.pdf