Phenotypic screening reveals a highly selective phthalimide-based compound with antileishmanial activity.

Pharmacophores such as hydroxyethylamine (HEA) and phthalimide (PHT) have been identified as potential synthons for the development of compounds against various parasitic infections. In order to further advance our progress, we conducted an experiment utilising a collection of PHT and HEA derivative...

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Bibliographic Details
Main Authors: Farnaz Zahedifard, Meenakshi Bansal, Neha Sharma, Sumit Kumar, Siqi Shen, Priyamvada Singh, Brijesh Rathi, Martin Zoltner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0012050&type=printable