Design and Evaluation of Engineered Extracellular Vesicle (EV)-Based Targeting for EGFR-Overexpressing Tumor Cells Using Monobody Display

Background: Extracellular vesicles (EVs) are attracting interest as a new class of drug delivery vehicles due to their intrinsic nature of biomolecular transport in the body. We previously demonstrated that EV surface modification with tissue-specific molecules accomplished targeted EV-mediated DNA...

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Bibliographic Details
Main Authors: Hiroaki Komuro, Shakhlo Aminova, Katherine Lauro, Daniel Woldring, Masako Harada
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/9/2/56