Celastrol and Melatonin Modify <i>SIRT1</i>, <i>SIRT6</i> and <i>SIRT7</i> Gene Expression and Improve the Response of Human Granulosa-Lutein Cells to Oxidative Stress

An excess of oxidative stress (OS) may affect several physiological processes fundamental to reproduction. SIRT1, SIRT6 and SIRT7 are involved in protection stress systems caused by OS, and they can be activated by antioxidants such as celastrol or melatonin. In this study, we evaluate <i>SIRT...

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Bibliographic Details
Main Authors: Rita Martín-Ramírez, Rebeca González-Fernández, Jairo Hernández, Pablo Martín-Vasallo, Angela Palumbo, Julio Ávila
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/12/1871