Anaplastic lymphoma kinase (ALK) gene alteration in signet ring cell carcinoma of the gastrointestinal tract

Objectives: ALK-EML4 translocation is an established driver aberration in non-small cell lung cancer (NSCLC), with reported predilection for cases with signet ring histology. We assessed the presence of anaplastic lymphoma kinase (ALK) gene rearrangements in signet ring cancers arising in the stomac...

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Main Authors: Olatunji B. Alese, Bassel F. El-Rayes, Gabriel Sica, Guojing Zhang, Dianne Alexis, Francisco G. La Rosa, Marileila Varella-Garcia, Zhengjia Chen, Michael R. Rossi, Nazim V. Adsay, Fadlo R. Khuri, Taofeek K. Owonikoko
Format: Article
Language:English
Published: SAGE Publishing 2015-03-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758834014567117