Developmental morphogens direct human induced pluripotent stem cells toward an annulus fibrosus‐like cell phenotype

Developmental morphogens direct human induced pluripotent stem cells toward an annulus fibrosus‐like cell phenotype

Abstract Introduction Therapeutic interventions for intervertebral disc herniation remain scarce due to the inability of endogenous annulus fibrosus (AF) cells to respond to injury and drive tissue regeneration. Unlike other orthopedic tissues, such as cartilage, delivery of exogenous cells to the s...

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Bibliographic Details
Main Authors: Ana P. Peredo, Tonia K. Tsinman, Edward D. Bonnevie, Xi Jiang, Harvey E. Smith, Sarah E. Gullbrand, Nathaniel A. Dyment, Robert L. Mauck
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:JOR Spine
Subjects:
culture systems
regenerative medicine
stem cell
Online Access:https://doi.org/10.1002/jsp2.1313

Internet

https://doi.org/10.1002/jsp2.1313

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