Three-dimensional label-free histological imaging of whole organs by microtomy-assisted autofluorescence tomography

Summary: Three-dimensional (3D) histology is vitally important to characterize disease-induced tissue heterogeneity at the individual cell level. However, it remains challenging for both high-throughput 3D imaging and volumetric reconstruction. Here we propose a label-free, cost-effective, and ready...

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Bibliographic Details
Main Authors: Yan Zhang, Lei Kang, Wentao Yu, Victor T.C. Tsang, Terence T.W. Wong
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221016916