Bioinformatic identification and experiment validation reveal 6 hub genes, promising diagnostic and therapeutic targets for Alzheimer’s disease

Bioinformatic identification and experiment validation reveal 6 hub genes, promising diagnostic and therapeutic targets for Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disease that can cause dementia. We aim to screen out the hub genes involved in AD based on microarray datasets. Methods Gene expression profiles GSE5281 and GSE28146 were retrieved from Gene Expression Omnibus database...

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Bibliographic Details
Main Authors: Wenyuan Cao, Zhangge Ji, Shoulian Zhu, Mei Wang, Runming Sun
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Medical Genomics
Subjects:
Alzheimer disease
Gene expression profiling
Protein interaction maps
Computational biology
Online Access:https://doi.org/10.1186/s12920-023-01775-6

Internet

https://doi.org/10.1186/s12920-023-01775-6

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