Naringenin and Quercetin Exert Contradictory Cytoprotective and Cytotoxic Effects on Tamoxifen-Induced Apoptosis in HepG2 Cells

Naringenin and Quercetin Exert Contradictory Cytoprotective and Cytotoxic Effects on Tamoxifen-Induced Apoptosis in HepG2 Cells

Tamoxifen is commonly used to treat estrogen receptor-positive breast cancer and hepatocellular carcinoma. Phytoconstituents are considered candidates for chemopreventive drugs in cancer treatment. However, it remains unknown what would happen if tamoxifen and phytoconstituents were administrated si...

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Bibliographic Details
Main Authors: Zhixiang Xu, Yue Jia, Jun Liu, Xiaomin Ren, Xiaoxia Yang, Xueshan Xia, Xuejun Pan
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Nutrients
Subjects:
hepatotoxicity
double dose-response
tamoxifen
naringenin
quercetin
apoptosis
Online Access:https://www.mdpi.com/2072-6643/14/24/5394

Internet

https://www.mdpi.com/2072-6643/14/24/5394

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