Intrinsic braking role of descending locus coeruleus noradrenergic neurons in acute and chronic itch in mice

Intrinsic braking role of descending locus coeruleus noradrenergic neurons in acute and chronic itch in mice

Abstract Itch is defined as an unpleasant sensation that provokes a desire to scratch. Our understanding of neuronal circuits for itch information transmission and processing in the spinal dorsal horn (SDH) has progressively advanced following the identification of SDH neuron subsets that are crucia...

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Bibliographic Details
Main Authors: Keisuke Koga, Yuto Shiraishi, Ryo Yamagata, Hidetoshi Tozaki-Saitoh, Miho Shiratori-Hayashi, Makoto Tsuda
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Molecular Brain
Subjects:
Descending noradrenaline neurons
Locus coeruleus
Spinal dorsal horn
Gastrin-releasing peptide receptor-expressing neurons
Itch
Mouse
Online Access:http://link.springer.com/article/10.1186/s13041-020-00688-0

Internet

http://link.springer.com/article/10.1186/s13041-020-00688-0

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