Dissection of key factors correlating with H5N1 avian influenza virus driven inflammatory lung injury of chicken identified by single-cell analysis.

Dissection of key factors correlating with H5N1 avian influenza virus driven inflammatory lung injury of chicken identified by single-cell analysis.

Chicken lung is an important target organ of avian influenza virus (AIV) infection, and different pathogenic virus strains lead to opposite prognosis. Using a single-cell RNA sequencing (scRNA-seq) assay, we systematically and sequentially analyzed the transcriptome of 16 cell types (19 clusters) in...

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Bibliographic Details
Main Authors: Manman Dai, Sufang Zhu, Zhihao An, Bowen You, Ziwei Li, Yongxiu Yao, Venugopal Nair, Ming Liao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-10-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011685&type=printable

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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011685&type=printable

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