Immune cells mediate the causal relationship between uveitis and colorectal cancer via Mendelian randomization analysis

Immune cells mediate the causal relationship between uveitis and colorectal cancer via Mendelian randomization analysis

Abstract Colorectal cancer (CRC) is one of the most common and deadly malignancies worldwide, and immune regulation plays a critical role in its development. This study investigates the causal relationships between uveitis, specific immune cell traits, and CRC using Mendelian Randomization (MR) anal...

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Bibliographic Details
Main Authors: Li Zhou, Jiwang Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Mendelian randomization
uveitis
colorectal cancer
immune cells
levels of extracellular monocyte HLA-DR expression
mediator
Online Access:https://doi.org/10.1038/s41598-024-77758-z

Internet

https://doi.org/10.1038/s41598-024-77758-z

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