Amentoflavone Exerts Anti-Neuroinflammatory Effects by Inhibiting TLR4/MyD88/NF-κB and Activating Nrf2/HO-1 Pathway in Lipopolysaccharide-Induced BV2 Microglia

Background. Amentoflavone, a natural biflavone, exerts anti-inflammation, antioxidation, and antiapoptosis effects on many diseases. However, the mechanism of amentoflavone on neuroinflammation-related diseases has not been comprehensively examined clearly. Methods. BV2 microglial cells were treated...

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Bibliographic Details
Main Authors: Shikuo Rong, Chunrong Yang, Feng Wang, Yiyang Wu, Kuishen Sun, Tao Sun, Zeyu Wu
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2022/5184721