Optimization of Transcription Factor Genetic Circuits

Optimization of Transcription Factor Genetic Circuits

Transcription factors (TFs) affect the production of mRNAs. In essence, the TFs form a large computational network that controls many aspects of cellular function. This article introduces a computational method to optimize TF networks. The method extends recent advances in artificial neural network...

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Bibliographic Details
Main Author: Steven A. Frank
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biology
Subjects:
genetic regulatory networks
transcription factors
optimization
differential equation models
artificial neural networks
automatic differentiation
Online Access:https://www.mdpi.com/2079-7737/11/9/1294

Internet

https://www.mdpi.com/2079-7737/11/9/1294

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