Prophylactic Hydroxyurea Treatment Is Associated with Improved Cerebral Hemodynamics as a Surrogate Marker of Stroke Risk in Sickle Cell Disease: A Retrospective Comparative Analysis

Prophylactic Hydroxyurea Treatment Is Associated with Improved Cerebral Hemodynamics as a Surrogate Marker of Stroke Risk in Sickle Cell Disease: A Retrospective Comparative Analysis

Sickle cell disease (SCD) increases the incidence of childhood stroke eighty-fold. Stroke risk can be estimated by measurement of the blood velocity through the middle cerebral artery (MCA) using transcranial doppler ultrasound (TCD). A high MCA blood velocity indicates increased stroke risk due to...

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Bibliographic Details
Main Authors: Brian R. Peine, Michael U. Callaghan, Joseph H. Callaghan, Alexander K. Glaros
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Journal of Clinical Medicine
Subjects:
sickle
ischemic
stroke
trans cranial doppler
average maximum mean velocity
Hydroxyurea
Online Access:https://www.mdpi.com/2077-0383/11/12/3491

Internet

https://www.mdpi.com/2077-0383/11/12/3491

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