Shifting the paradigm: engaging multicellular networks for cancer therapy

Abstract Most anti-cancer modalities are designed to directly kill cancer cells deploying mechanisms of action (MOAs) centered on the presence of a precise target on cancer cells. The efficacy of these approaches is limited because the rapidly evolving genetics of neoplasia swiftly circumvents the M...

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Bibliographic Details
Main Authors: Joyce Hu, Paolo Ascierto, Alessandra Cesano, Volker Herrmann, Francesco M. Marincola
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-024-05043-8