DNA methylation and single-nucleotide polymorphisms in DDX58 are associated with hand, foot and mouth disease caused by enterovirus 71.

<h4>Background</h4>This research aimed to explore the association between the RIG-I-like receptor (RIG-I and MDA5 encoded by DDX58 and IFIH1, respectively) pathways and the risk or severity of hand, foot, and mouth disease caused by enterovirus 71 (EV71-HFMD). In this context, we explore...

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Bibliographic Details
Main Authors: Ya-Ping Li, Chen-Rui Liu, Hui-Ling Deng, Mu-Qi Wang, Yan Tian, Yuan Chen, Yu-Feng Zhang, Shuang-Suo Dang, Song Zhai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010090