Metabolic Adaptions/Reprogramming in Islet Beta-Cells in Response to Physiological Stimulators—What Are the Consequences

Metabolic Adaptions/Reprogramming in Islet Beta-Cells in Response to Physiological Stimulators—What Are the Consequences

Irreversible pancreatic β-cell damage may be a result of chronic exposure to supraphysiological glucose or lipid concentrations or chronic exposure to therapeutic anti-diabetic drugs. The β-cells are able to respond to blood glucose in a narrow concentration range and release insulin in response, fo...

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Bibliographic Details
Main Authors: Philip Newsholme, Jordan Rowlands, Roselyn Rose’Meyer, Vinicius Cruzat
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Antioxidants
Subjects:
insulin
metabolic reprogramming
antidiabetic therapeutics
glucose metabolism
lipid metabolism
islet inflammation
Online Access:https://www.mdpi.com/2076-3921/11/1/108

Internet

https://www.mdpi.com/2076-3921/11/1/108

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