Investigating the physiological relevance of ex vivo disc organ culture nutrient microenvironments using in silico modeling and experimental validation
Abstract Background Ex vivo disc organ culture systems have become a valuable tool for the development and pre‐clinical testing of potential intervertebral disc (IVD) regeneration strategies. Bovine caudal discs have been widely selected due to their large availability and comparability to human IVD...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-06-01
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Series: | JOR Spine |
Subjects: | |
Online Access: | https://doi.org/10.1002/jsp2.1141 |