Effect of Nuclear Export Inhibitor Leptomycin B on the Intracellular Localization of HBV Core Protein into Hepatocytes Cell Line Huh-7 and HepG2 Cells

Leptomycin B (LMB) was originally discovered as a potent anti-fungal antibiotic from Streptomyces species. The cellular target of LMB has been identified as the nuclear export receptor CRM-1 or exportin-1, which is involved in nuclear trafficking of cellular RNAs or proteins containing the nuclear e...

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Bibliographic Details
Main Authors: Aris Haryanto, Nastiti Wijayanti, Michael Kann
Format: Article
Language:English
Published: Universitas Gadjah Mada, Yogyakarta 2010-12-01
Series:Indonesian Journal of Biotechnology
Online Access:https://jurnal.ugm.ac.id/ijbiotech/article/view/7823