Evaluating the influence of common antibiotics on the efficacy of a recombinant immunotoxin in tissue culture

Evaluating the influence of common antibiotics on the efficacy of a recombinant immunotoxin in tissue culture

Abstract Objective Recombinant immunotoxins (RITs) are antibody-toxin fusion proteins that can selectively eliminate populations of cells expressing specific surface receptors. They are in evaluation as therapeutic agents for cancer. RITs based on Pseudomonas exotoxin A (PE) are in use clinically fo...

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Bibliographic Details
Main Authors: Yuyi Zhu, John E. Weldon
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Research Notes
Subjects:
Recombinant immunotoxins
Combination therapy
Antibiotics
HB21-LR
Pseudomonas exotoxin A
Cytotoxicity
Online Access:http://link.springer.com/article/10.1186/s13104-019-4337-6

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http://link.springer.com/article/10.1186/s13104-019-4337-6

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