Mechanistic insights from animal models of neurofibromatosis type 1 cognitive impairment

Mechanistic insights from animal models of neurofibromatosis type 1 cognitive impairment

Neurofibromatosis type 1 (NF1) is an autosomal-dominant neurogenetic disorder caused by mutations in the gene neurofibromin 1 (NF1). NF1 predisposes individuals to a variety of symptoms, including peripheral nerve tumors, brain tumors and cognitive dysfunction. Cognitive deficits can negatively impa...

Full description

Bibliographic Details
Main Authors: Andrew H. Miller, Mary C. Halloran
Format: Article
Language:English
Published: The Company of Biologists 2022-08-01
Series:Disease Models & Mechanisms
Subjects:
neurofibromatosis
neurofibromin
ras signaling
camp signaling
Online Access:http://dmm.biologists.org/content///dmm049422

Internet

http://dmm.biologists.org/content///dmm049422

Similar Items