A novel copper chelate modulates tumor associated macrophages to promote anti-tumor response of T cells.

<h4>Background</h4>At the early stages of carcinogenesis, the induction of tumor specific T cell mediated immunity seems to block the tumor growth and give protective anti-tumor immune response. However, tumor associated macrophages (TAMs) might play an immunosuppressive role and subvert...

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Main Authors: Shilpak Chatterjee, Ananda Mookerjee, Jayati Mookerjee Basu, Paramita Chakraborty, Avishek Ganguly, Arghya Adhikary, Debanjan Mukhopadhyay, Sudipto Ganguly, Rajdeep Banerjee, Mohammad Ashraf, Jaydip Biswas, Pradeep K Das, Gourisankar Sa, Mitali Chatterjee, Tanya Das, Soumitra Kumar Choudhuri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19756150/?tool=EBI