Releasing the Immune System Brakes Using siRNAs Enhances Cancer Immunotherapy

Therapeutic dendritic cell (DC) cancer vaccines rely on the immune system to eradicate tumour cells. Although tumour antigen-specific T cell responses have been observed in most studies, clinical responses are fairly low, arguing for the need to improve the design of DC-based vaccines. The incorpora...

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Bibliographic Details
Main Author: Mouldy Sioud
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/2/176