The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment
Aortic valves (AVs) undergo unique stretch histories that include high rates and magnitudes. While major differences in deformation patterns have been observed between normal and congenitally defective bicuspid aortic valves (BAVs), the relation to underlying mechanisms of rapid disease onset in BAV...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2023-06-01
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Series: | APL Bioengineering |
Online Access: | http://dx.doi.org/10.1063/5.0138030 |