PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells

PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells

Filopodia, a finger-like structure and actin-rich plasma-membrane protrusion at the leading edge of the cell, has important roles in cell motility. However, the mechanisms of filopodia generation are not well-understood via the actin-related protein 2/3 (ARP2/3) complex in Non-Small Cell Lung Cancer...

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Bibliographic Details
Main Authors: Zhili Wei, Ru Wang, Xun Yin, lian Zhang, Yunlong Lei, Ying Zhang, Yi Li, Jiaqian Wu, Youquan Bu, Guoxiang Jin, Chundong Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-01-01
Series:Genes and Diseases
Subjects:
ARP2/3 complex
Cell motility
FAK
Filopodia
Focal adhesion
Integrin
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304221000325

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http://www.sciencedirect.com/science/article/pii/S2352304221000325

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