Heterocycles 52: The Drug-Likeness Analysis of Anti-Inflammatory Thiazolo[3,2-b][1,2,4]triazole and Imidazo[2,1-b][1,3,4]thiadiazole Derivatives

Heterocycles 52: The Drug-Likeness Analysis of Anti-Inflammatory Thiazolo[3,2-b][1,2,4]triazole and Imidazo[2,1-b][1,3,4]thiadiazole Derivatives

Lipophilicity, a significant physicochemical parameter of bioactive molecules, along with absorption, distribution, metabolism, excretion parameters and toxicity risk, was investigated for 32 thiazolo[3,2-b][1,2,4]triazole and imidazo[2,1-b][1,3,4]thiadiazole derivatives with anti-inflammatory poten...

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Bibliographic Details
Main Authors:	Anamaria Apan, Dorina Casoni, Denisa Leonte, Cristina Pop, Irina Iaru, Cristina Mogoșan, Valentin Zaharia
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Series:	Pharmaceuticals
Subjects:	lipophilicity RP-TLC ADME properties bioactivity thiazolo[3,2-b][1,2,4]triazoles imidazo[2,1-b][1,3,4]thiadiazoles
Online Access:	https://www.mdpi.com/1424-8247/17/3/295

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