Eravacycline susceptibility was impacted by genetic mutation of 30S ribosome subunits, and branched-chain amino acid transport system II carrier protein, Na/Pi cotransporter family protein in Staphylococcus aureus

Eravacycline susceptibility was impacted by genetic mutation of 30S ribosome subunits, and branched-chain amino acid transport system II carrier protein, Na/Pi cotransporter family protein in Staphylococcus aureus

Abstract Background Our previous research indicated the excellent in vitro antibacterial activity of Eravacycline (Erava) and its heteroresistance frequency against clinical Staphylococcus aureus isolates. In this study, we further aimed to investigate the mechanisms of Erava resistance and heterore...

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Bibliographic Details
Main Authors: Zhanwen Wang, Zhiwei Lin, Bing Bai, Guangjian Xu, Peiyu Li, Zhijian Yu, Qiwen Deng, Yongpeng Shang, Jinxin Zheng
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Microbiology
Subjects:
Eravacycline
Staphylococcus aureus
Antimicrobial agent
Antimicrobial activity
Online Access:http://link.springer.com/article/10.1186/s12866-020-01869-6

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http://link.springer.com/article/10.1186/s12866-020-01869-6

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