Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts

<p>Abstract</p> <p>Background</p> <p>Antiangiogenic agents that disrupt the vascular endothelial growth factor pathway have been demonstrated to normalize tumor vasculature and improve tumor oxygenation in some studies and to induce hypoxia in others. The aim of this pr...

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Bibliographic Details
Main Authors: Gaustad Jon-Vidar, Simonsen Trude G, Leinaas Marit N, Rofstad Einar K
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/12/388