Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly

Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly

Abstract For successful infection of host cells and virion production, enveloped viruses, including Zika virus (ZIKV), extensively rely on cellular lipids. However, how virus protein–lipid interactions contribute to the viral life cycle remains unclear. Here, we employ a chemo-proteomics approach wi...

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Bibliographic Details
Main Authors: Sarah Goellner, Giray Enkavi, Vibhu Prasad, Solène Denolly, Sungmin Eu, Giulia Mizzon, Leander Witte, Waldemar Kulig, Zina M. Uckeley, Teresa M. Lavacca, Uta Haselmann, Pierre-Yves Lozach, Britta Brügger, Ilpo Vattulainen, Ralf Bartenschlager
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42985-x

Internet

https://doi.org/10.1038/s41467-023-42985-x

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