Stroma-derived miR-214 coordinates tumor dissemination

Stroma-derived miR-214 coordinates tumor dissemination

Abstract Background Tumor progression is based on a close interaction between cancer cells and Tumor MicroEnvironment (TME). Here, we focus on the role that Cancer Associated Fibroblasts (CAFs), Mesenchymal Stem Cells (MSCs) and microRNAs (miRs) play in breast cancer and melanoma malignancy. Methods...

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Bibliographic Details
Main Authors: Francesca Orso, Federico Virga, Daniela Dettori, Alberto Dalmasso, Mladen Paradzik, Aurora Savino, Margherita A. C. Pomatto, Lorena Quirico, Stefania Cucinelli, Martina Coco, Katia Mareschi, Franca Fagioli, Leonardo Salmena, Giovanni Camussi, Paolo Provero, Valeria Poli, Massimiliano Mazzone, Pier Paolo Pandolfi, Daniela Taverna
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
miR-214
Stroma
Extracellular vesicles (EVs)
Crosstalk
Metastasis formation
IL-6
Online Access:https://doi.org/10.1186/s13046-022-02553-5

Internet

https://doi.org/10.1186/s13046-022-02553-5

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