Oxidation of LDL by rabbit and human 15-lipoxygenase: prevalence of nonenzymatic reactions
15-Lipoxygenase (15-LO)-induced oxidation of lipids in human LDL may be pro-atherogenic. However, the extent to which 15-LO promotes enzymatic oxidation of esterified (i.e., major) lipids in LDL may depend on various factors. Here, we show that overall, LDL lipid oxidation was favored with high acti...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2001-07-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520315972 |