Pocket CLARITY enables distortion-mitigated cardiac microstructural tissue characterization of large-scale specimens

Pocket CLARITY enables distortion-mitigated cardiac microstructural tissue characterization of large-scale specimens

Molecular phenotyping by imaging of intact tissues has been used to reveal 3D molecular and structural coherence in tissue samples using tissue clearing techniques. However, clearing and imaging of cardiac tissue remains challenging for large-scale (>100 mm3) specimens due to sample distortio...

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Bibliographic Details
Main Authors: Joan J. H. Kim, Shestruma Parajuli, Aman Sinha, Mohammed Mahamdeh, Maaike van den Boomen, Jaume Coll-Font, Lily Shi Chen, Yiling Fan, Robert A. Eder, Kellie Phipps, Shiaulou Yuan, Christopher Nguyen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
CLARITY
helicity
microstructure
distortion
lightsheet microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1037500/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.1037500/full

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