Safety and feasibility of virus-specific T cells derived from umbilical cord blood in cord blood transplant recipients

Safety and feasibility of virus-specific T cells derived from umbilical cord blood in cord blood transplant recipients

Abstract: Adoptive transfer of virus-specific T cells (VSTs) has been shown to be safe and effective in stem cell transplant recipients. However, the lack of virus-experienced T cells in donor cord blood (CB) has prevented the development of ex vivo expanded donor-derived VSTs for recipients of this...

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Main Authors: Allistair A. Abraham, Tami D. John, Michael D. Keller, C. Russell N. Cruz, Baheyeldin Salem, Lauren Roesch, Hao Liu, Fahmida Hoq, Bambi J. Grilley, Adrian P. Gee, Hema Dave, David A. Jacobsohn, Robert A. Krance, Elizabeth. J. Shpall, Caridad A. Martinez, Patrick J. Hanley, Catherine M. Bollard
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920306406

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http://www.sciencedirect.com/science/article/pii/S2473952920306406

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