The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells

The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells

Abstract Background MicroRNAs are a group of small non-coding RNAs that are involved in development and diseases such as cancer. Previously, we demonstrated that miR-335 is crucial for preventing collagen type XI alpha 1 (COL11A1)-mediated epithelial ovarian cancer (EOC) progression and chemoresista...

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Bibliographic Details
Main Authors: Yi-Hui Wu, Yu-Fang Huang, Pei-Ying Wu, Tzu-Hao Chang, Soon-Cen Huang, Cheng-Yang Chou
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Ovarian Research
Subjects:
Epithelial ovarian carcinoma
Collagen type XI alpha 1
miR-509-3p
DNMT1
Online Access:https://doi.org/10.1186/s13048-023-01191-5

Internet

https://doi.org/10.1186/s13048-023-01191-5

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