Clinical Overestimation of HER2 Positivity in Early Estrogen and Progesterone Receptor–Positive Breast Cancer and the Value of Molecular Subtyping Using BluePrint

Purpose: Human epidermal growth factor receptor 2 (HER2) positivity is an important prognostic and predictive indicator in breast cancer. HER2 status is determined by immunohistochemistry and fluorescent in situ hybridization (FISH), which are potentially inaccurate techniques as a result of several...

Full description

Bibliographic Details
Main Authors: Ettienne J. Myburgh, Lizanne Langenhoven, Kathleen A. Grant, Lize van der Merwe, Maritha J. Kotze
Format: Article
Language:English
Published: American Society of Clinical Oncology 2017-08-01
Series:Journal of Global Oncology
Online Access:http://ascopubs.org/doi/10.1200/JGO.2016.006072