Hypoxic microenvironment as a crucial factor triggering events leading to rupture of intracranial aneurysm

Abstract Subarachnoid hemorrhage being the rupture of intracranial aneurysm (IA) as a major cause has quite poor prognosis, despite the modern technical advances. Thereby, the mechanisms underlying the rupture of lesions should be clarified. Recently, we and others have clarified the formation of va...

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Bibliographic Details
Main Authors: Isao Ono, Tomomichi Kayahara, Akitsugu Kawashima, Akihiro Okada, Susumu Miyamoto, Hiroharu Kataoka, Hiroki Kurita, Akira Ishii, Tomohiro Aoki
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32001-z