mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons

mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons

Abstract Plasticity of principal cells and inhibitory interneurons underlies hippocampal memory. Bidirectional modulation of somatostatin cell mTORC1 activity, a crucial translational control mechanism in synaptic plasticity, causes parallel changes in hippocampal CA1 somatostatin interneuron (SOM-I...

Full description

Bibliographic Details
Main Authors: François-Xavier Michon, Isabel Laplante, Anthony Bosson, Richard Robitaille, Jean-Claude Lacaille
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Molecular Brain
Subjects:
Hippocampus
Somatostatin interneuron
In vivo 2-photon Ca2+ imaging
Mechanistic target of rapamycin complex 1 (mTORC1)
Virtual reality
Spatial memory task
Online Access:https://doi.org/10.1186/s13041-023-01042-w

Internet

https://doi.org/10.1186/s13041-023-01042-w

Similar Items