Upregulation of Phospholipase D Expression and Activation in Ventricular Pressure-Overload Hypertrophy

Evidence for a role of phospholipase D (PLD) in cellular proliferation and differentiation is accumulating. We studied PLD activity and expression in normal and hypertrophic rat and human hearts. In rat heart, abdominal aortic banding (constriction to 50% of original lumen) caused hypertrophy in the...

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Bibliographic Details
Main Authors: Ali A. Peivandi, Alexander Huhn, Hans-Anton Lehr, Shenchu Jin, Joachim Troost, Sonia Salha, Tobias Weismüller, Konrad Löffelholz
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319321772