New genetic variants of LATS1 detected in urinary bladder and colon cancer

New genetic variants of LATS1 detected in urinary bladder and colon cancer

LATS1, the large tumor suppressor 1 gene, encodes for a serine/threonine kinase protein and is implicated in cell cycle progression. LATS1 is down-regulated in various human cancers, such as breast cancer, and astrocytoma. Point mutations in LATS1 were reported in human sarcomas. Additionally, loss...

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Bibliographic Details
Main Authors: Mona Kamal Saadeldin, Heba eShawer, Ahmed eMostafa, Neemat Mohamed Kassem, Asma eAmleh, Rania eSiam
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Genetics
Subjects:
SNP
Colon Cancer
tumor suppressor
Urinary Bladder Cancer
LATS1
Egyptian patients
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00425/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00425/full

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