ReCARving the future: bridging CAR T-cell therapy gaps with synthetic biology, engineering, and economic insights

Chimeric antigen receptor (CAR) T-cell therapy has revolutionized the treatment of hematologic malignancies, offering remarkable remission rates in otherwise refractory conditions. However, its expansion into broader oncological applications faces significant hurdles, including limited efficacy in s...

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Bibliographic Details
Main Authors: Alaa Ali, John F. DiPersio
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1432799/full