Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell RNA sequencing

Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell RNA sequencing

Early identification of resistant cancer cells is currently a major challenge, as their expansion leads to refractoriness. To capture the dynamics of these cells, we made a comprehensive analysis of disease progression and treatment response in a chronic lymphocytic leukemia (CLL) patient using a co...

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Bibliographic Details
Main Authors: Terezia Kurucova, Kamila Reblova, Pavlina Janovska, Jakub Pawel Porc, Veronika Navrkalova, Sarka Pavlova, Jitka Malcikova, Karla Plevova, Boris Tichy, Michael Doubek, Vitezslav Bryja, Jana Kotaskova, Sarka Pospisilova
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Molecular Oncology
Subjects:
CLL
clonal evolution
rare subpopulation
refractoriness
single‐cell RNA sequencing
Online Access:https://doi.org/10.1002/1878-0261.13663

Internet

https://doi.org/10.1002/1878-0261.13663

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