Oxidative stress as a key modulator of cell fate decision in osteoarthritis and osteoporosis: a narrative review

Oxidative stress as a key modulator of cell fate decision in osteoarthritis and osteoporosis: a narrative review

Abstract During aging and after traumatic injuries, cartilage and bone cells are exposed to various pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated molecular patterns, and proinflammatory cytokines. This detrimental environment triggers cellular stress and subs...

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Bibliographic Details
Main Authors: Jana Riegger, Astrid Schoppa, Leonie Ruths, Melanie Haffner-Luntzer, Anita Ignatius
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cellular & Molecular Biology Letters
Subjects:
Osteoarthritis
Osteoporosis
Senescence
Oxidative stress
ROS
Cell death
Online Access:https://doi.org/10.1186/s11658-023-00489-y

Internet

https://doi.org/10.1186/s11658-023-00489-y

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