Pan-Cancer Prediction of Cell-Line Drug Sensitivity Using Network-Based Methods

Pan-Cancer Prediction of Cell-Line Drug Sensitivity Using Network-Based Methods

The development of reliable predictive models for individual cancer cell lines to identify an optimal cancer drug is a crucial step to accelerate personalized medicine, but vast differences in cancer cell lines and drug characteristics make it quite challenging to develop predictive models that resu...

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Bibliographic Details
Main Authors: Maryam Pouryahya, Jung Hun Oh, James C. Mathews, Zehor Belkhatir, Caroline Moosmüller, Joseph O. Deasy, Allen R. Tannenbaum
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
drug sensitivity
optimal mass transport
network-based clustering
cell lines
Online Access:https://www.mdpi.com/1422-0067/23/3/1074

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https://www.mdpi.com/1422-0067/23/3/1074

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