Generation of human elongating multi-lineage organized cardiac gastruloids

Summary: Human elongating multi-lineage organized (EMLOC) gastruloid technology captures key aspects of trunk neurodevelopment including neural integration with cardiogenesis. We generate multi-chambered, contractile EMLOC gastruloids with integrated central and peripheral neurons using defined cult...

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Bibliographic Details
Main Authors: Zachary T. Olmsted, Maria Belen Paredes-Espinosa, Janet L. Paluh
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672200778X