All-in-one glycol chitosan nanoparticles for co-delivery of doxorubicin and anti-PD-L1 peptide in cancer immunotherapy

All-in-one glycol chitosan nanoparticles for co-delivery of doxorubicin and anti-PD-L1 peptide in cancer immunotherapy

Synergistic immunotherapy of immune checkpoint blockade (ICB) and immunogenic cell death (ICD) has shown remarkable therapeutic efficacy in various cancers. However, patients show low response rates and undesirable outcomes to these combination therapies owing to the recycling mechanism of programme...

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Bibliographic Details
Main Authors: Sukyung Song, Man Kyu Shim, Suah Yang, Jaewan Lee, Wan Su Yun, Hanhee Cho, Yujeong Moon, Jin Young Min, Eun Hee Han, Hong Yeol Yoon, Kwangmeyung Kim
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-10-01
Series:Bioactive Materials
Subjects:
Chitosan nanoparticle
Synergistic immunotherapy
Immune checkpoint blockade
Multivalent binding
Immunogenic cell death
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23001688

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http://www.sciencedirect.com/science/article/pii/S2452199X23001688

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