Intrachromosomal Looping and Histone K27 Methylation Coordinately Regulates the lncRNA <i>H19</i>-Fetal Mitogen <i>IGF2</i> Imprinting Cluster in the Decidual Microenvironment of Early Pregnancy

Intrachromosomal Looping and Histone K27 Methylation Coordinately Regulates the lncRNA <i>H19</i>-Fetal Mitogen <i>IGF2</i> Imprinting Cluster in the Decidual Microenvironment of Early Pregnancy

Recurrent spontaneous abortion (RSA) is a highly heterogeneous complication of pregnancy with the underlying mechanisms remaining uncharacterized. Dysregulated decidualization is a critical contributor to the phenotypic alterations related to pregnancy complications. To understand the molecular fact...

Full description

Bibliographic Details
Main Authors: Xue Wen, Qi Zhang, Lei Zhou, Zhaozhi Li, Xue Wei, Wang Yang, Jiaomei Zhang, Hui Li, Zijun Xu, Xueling Cui, Songling Zhang, Yufeng Wang, Wei Li, Andrew R. Hoffman, Zhonghui Liu, Ji-Fan Hu, Jiuwei Cui
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
decidualization
recurrent spontaneous abortion
long noncoding RNA
epigenetics
H3K27 methylation
Online Access:https://www.mdpi.com/2073-4409/11/19/3130

Internet

https://www.mdpi.com/2073-4409/11/19/3130

Similar Items