Parity is associated with long-term differences in DNA methylation at genes related to neural plasticity in multiple sclerosis

Parity is associated with long-term differences in DNA methylation at genes related to neural plasticity in multiple sclerosis

Abstract Background Pregnancy in women with multiple sclerosis (wwMS) is associated with a reduction of long-term disability progression. The mechanism that drives this effect is unknown, but converging evidence suggests a role for epigenetic mechanisms altering immune and/or central nervous system...

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Bibliographic Details
Main Authors: Maria Pia Campagna, Alexandre Xavier, Jim Stankovich, Vicki E. Maltby, Mark Slee, Wei Z. Yeh, Trevor Kilpatrick, Rodney J. Scott, Helmut Butzkueven, Jeannette Lechner-Scott, Rodney A. Lea, Vilija G. Jokubaitis
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Clinical Epigenetics
Subjects:
Pregnancy
Birth
Epigenetics
Neurodegeneration
Neuroplasticity
Online Access:https://doi.org/10.1186/s13148-023-01438-4

Internet

https://doi.org/10.1186/s13148-023-01438-4

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