Inhibition of PirB Activity by TAT-PEP Improves Mouse Motor Ability and Cognitive Behavior

Inhibition of PirB Activity by TAT-PEP Improves Mouse Motor Ability and Cognitive Behavior

Paired immunoglobulin-like receptor B (PirB), a functional receptor for myelin-associated inhibitory proteins, plays an important role in axon regeneration in injured brains. However, its role in normal brain function with age has not been previously investigated. Therefore in this study, we examine...

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Bibliographic Details
Main Authors: Ya-Jing Mi, Hai Chen, Na Guo, Meng-Yi Sun, Zhao-Hua Zhao, Xing-Chun Gao, Xiao-Long Wang, Rui-San Zhang, Jiang-Bing Zhou, Xing-Chun Gou
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
PirB
motor capacity
cognitive behavior
TAT-PEP
BDNF
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00199/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2017.00199/full

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